On Thursday and Friday, February 4-5, 2010, Professor J. Andrew Brown (Washington University in St. Louis) visited the Spanish and Portuguese Department at UCLA. On Thursday he gave a talk titled “Mashups and Digital Aesthetics in Edmundo Paz Soldán and Mike Wilson Reginato,” and on Friday he led the seminar “Cyborgs and Soundtracks: Studying Technology and Underground Culture in Ricardo Piglia's La ciudad ausente.” We took this opportunity to ask Professor Brown about his innovative work on science, literature, and popular culture. As Brown highlights in the interview, despite its current popularity, true interdisciplinary work is rare. This is what Brown has achieved throughout his career, and it makes his research fascinating both in terms of content and methodology.