To better understand provider experiences serving lesbian, gay, bisexual, transgender and Questioning (LGBTQ) runaway and homeless youth, this study reports on case studies of four local agencies receiving grants from the Administration for Children and Family’s Runaway and Homeless Youth (RHY) Program. The purpose of the study was to learn about programs’ strategies for identifying and serving LGBTQ RHY, the challenges programs face in understanding and addressing the needs of this population, and potential areas for future research. The report presents findings on four topics: (1) agencies’ collection and use of data on clients’ sexual orientation and gender identity, (2) providers’ assessment and perceptions of needs and capacities among LGBTQ RHY, (3) providers’ approaches to serving LGBTQ RHY, and (4) providers’ perceptions of research gaps and data needs related to services for LGBTQ RHY.