This study investigated the neural bases of event-related
semantic-memory deficits among people with aphasia due to
left-hemisphere (LH) stroke. A novel task using naturalistic
photographic stimuli and patient-friendly procedures was
used to test event-related semantic knowledge. In the task,
participants decided whether depicted events were normal
(represented in semantic memory) or were abnormal (not
represented in semantic memory). Performance on this Event
task was correlated with deficits in action- and object-concept
processing and on standardized language measures, especially
action- and verb-processing deficits. Logistic regression
analyses examined lesion correlates of patient performance on
the Event task. Surprisingly, increasing LH lesion size in
action ROIs was associated with improved performance on
the event-knowledge task. These findings suggest that action
processing may play a special role in event-related semantic
memory representations. Furthermore, they are consistent
with recent claims that the right hemisphere may be
especially important for activation of event-related
knowledge.