Angioplasmocellular hyperplasia is a rare clinical condition with blood vessel proliferation and a reactive plasma cell infiltrate. To the best of our knowledge fewer than 20 cases of cutaneous angioplasmocellular hyperplasia have been published in English literature. We report a case of a 65-year-old man who presented with a long standing asymptomatic flesh colored ulcerated nodule on the back. Histopathological examination revealed a dermal vascular proliferation with polyclonal plasma cell infiltration. A diagnosis of angioplasmocellular hyperplasia was established. This entity is rare and we would like to emphasize the importance of clinico-pathological correlation to differentiate it from various other conditions of cutaneous plasma cell infiltration.