China’s remarkable rise as an international technology and innovation powerhouse comes courtesy of domestic efforts to upgrade its scientific enterprise. In this brief, Cong Cao, a professor in innovation studies at Nottingham University Ningbo China, argues that the globalization of science has also played a significant role, fostering links between Chinese and international researchers, allowing Chinese students to study abroad, and attracting foreign direct investment to China’s research sector. However, as pressures in Western countries to decouple from China mount, the future of China’s science, technology, and innovation system faces strong headwinds.