In this article, a Modernist and a Renaissance art historian analyze the 1949 exhibition of Renaissance domestic painting at the Palazzo Strozzi in Florence. Based on unpublished documents at the Ragghianti foundation in Lucca, we trace the genesis, development, and installation of the show, as well as responses to it on the part of the scholarly community and in the popular press. We look at a variety of interests that drove the planners, ranging from postwar politics, historic reconstruction, museology, local economy and tourism, to changing definitions of the family and women’s roles in the home. Finally, we uncover a link between the 1949 show and the establishment of the Palazzo Davanzati museum.