- Liu, Kathleen;
- Orme, RML;
- Perkins, GD;
- McAuley, DF;
- Liu, KD;
- Mason, AJ;
- Morelli, A;
- Singer, M;
- Ashby, D;
- Gordon, AC
Background: Organ dysfunction consequent to infection ('severe sepsis') is the leading cause of admission to an intensive care unit (ICU). In both animal models and early clinical studies the calcium channel sensitizer levosimendan has been demonstrated to