Treatment

EV Case

Response

Recurrence

Authors

Acitretin (0.5-1mg/kg/day) for 6 months 

25 year old female

Partial

Yes

Iraji et al [15]

Etretinate (1mg/kg/day) for 4 months

4 patients (ages 31-52)

Partial

Yes

Lutzner et al [16]

Etretinate (1-1.5 mg/kg/day)

14 year old female

Partial

Lost to follow up

Al Rubaie et al [17]

Etretinate (1-1.5 mg/kg/day)

18 year old male

Partial

Yes

Al Rubaie et al [17]

Isotretinoin (0.8 mg/kg/day) for six months

20 year old male

Complete

Yes

Rallis et al [18]

Acitretin (0.75mg/kg/day) and Interferon alfa-2a (3 million IU 3 times a week) for 6 months.

19 year old female

Partial

Yes

Anadolu et al [18]

Acitretin, (0.2mg/kg/day) and pegylated interferon alfa-2b (1 µg/kg/week) for 12 months 

43 year old female with oral and genital squamous cell carcinomas

Partial

Yes

Development of Perianal Bowen Disease

Gubinelli et al [7]

Imiquimod (5 times a week) for 3 months

22 year old male with squamous cell carcinomas

Partial

Lost to follow up

Berthelot et al [21]

Imiquimod (5 times a week) and interferon alpha  (6 million IU twice a week ) for 17 weeks   

52 year old male with Bowen’s disease

Complete

No

Baskan et al [22]

Cimetidine (40mg/kg/day) for 3 months

16 year old male

Complete

No

Micali et al [23]  

Cimetidine  (40mg/k/day) for 6 months

8 female patients (15-40 years of age)

  3: Partial

  5: None

Yes

De Olivera et al [24]

5-aminolaevulinic acid photodynamic therapy (1 session)

69 year old female

Complete

Yes

Karrer et al [25]