Light Source

Number of Patients

Lesion types

Dose/session

Frequency

Therapy Duration

Response

Length of

Follow-up

Relapse Rate

Level of Evidence

Reference

308 nm excimer laser

2

(31-48 years old)

2 AAP of scalp

300-2300 mJ/cm²

Weekly

9-11 weeks

CR in 2/2

5-18 months

None

Prospective case series

Gundogan et al [29]

308 nm excimer laser

9

(12-56 years old)

5 refractory AAP of scalp

1 refractory AT

3 refractory AU

50-600 mJ/cm²

2 times/week

12 weeks

CR/PR in 5/5

NR

NR

3 months

None

Intra-individual prospective cohort

Zakaria et al [30]

308 nm excimer laser

1

(22 years old)

1 refractory AAP of scalp

200-4000 mJ/cm²

2 times/week

12 weeks

CR in 1/1

6 months

None

Side-by-side prospective cohort

Raulin et al [33]

308 nm excimer laser

18

(11-41 years old)

17 refractory AAP of scalp

10 refractory AAP of beard

7 refractory AAP of arms

7 refractory AAP of legs

1 refractory AT

50 - 600 mJ/cm²

2 times/week

12 weeks

CR in 13/17

PR in 4/10

NR

NR

NR

6 months

2/13 of CR

Intra-individual prospective cohort

Al-Mutairi et al [31]

308 nm excimer laser

11

(4-14 years old)

22 refractory AAP of scalp

4 refractory AAP of arms

4 refractory AAP of legs

2 refractory AT

50 - 600 mJ/cm²

2 times/week

12 weeks

CR/PR in 18/30

NR

NR

NR

6 months

4/18 of CR/PR

Intra-individual prospective cohort

Al-Mutairi et al [32]

308 nm excimer light

8

--

8 refractory alopecia areata

--

Weekly

Up to 10 weeks

CR in 4/8

6 months

None

Prospective case series

Aubin et al [34]

904 nm infrared diode laser

16

(4-50 years old)

14 refractory AAP of scalp

6 refractory AAP of eyebrow

12 refractory AAP of beard

2 refractory AAP of moustache

Up to 150 W, 40/s

Weekly

4 weeks

CR/PR in 14/14

CR in 5/6

CR in 11/12

PR in 2/2

2 months

None

Intra-individual prospective cohort

Waiz et al [36]

600-1600 nm infrared laser

15

(18-68 years old)

15 AAP of the scalp

1.8 W, 4/s

Weekly or 2 times/week

2-20 weeks

PR in 7/15

--

--

Intra-individual prospective cohort

Yamazaki et al [35]

Fractional photothermolysis laser

1

(35 years old)

1 refractory AAP of scalp

10-15 mJ/cm²

Weekly

24 weeks

CR in 1/1

6 months

None

Prospective case report

Yoo et al [37]

AAP, alopecia areata partialis; AT, alopecia totalis; AU, alopecia universalis; CR, complete response; PR, partial response; NR, no response